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Updated: Jul 11, 2025

An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations
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An Allele-specific Gene Expression Assay to Test the Functional Basis of Genetic Associations

Published on: November 3, 2010

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在全球多样化的人类队列中基因表达变异的来源

Dylan J Taylor1, Surya B Chhetri2, Michael G Tassia1

  • 1Department of Biology, Johns Hopkins University, Baltimore MD, USA.

bioRxiv : the preprint server for biology
|November 15, 2023
PubMed
概括

遗传变异影响人类特征,但过去的研究缺乏多样性. 这种新的RNA-seq数据集揭示了基因表达和拼接模式在大多数情况下是跨种群共享的,为基因组进化提供了更具包容性的观点.

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Genetic Variation

Genetic variation is the diversity in DNA sequences found among individuals of the same species. This diversity is crucial for a species' survival because it helps organisms adapt to environmental changes. Genetic variation begins with fertilization, where an egg and sperm cell merge. Each of these cells carries 23 chromosomes, up to 46 in the fertilized egg. Chromosomes are long DNA strands that contain genes, the basic units of heredity.
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