COVID-19和肝脏:一个复杂而不断变化的图片
Simon D Taylor-Robinson1,2, Marsha Y Morgan3
1Department of Surgery and Cancer, Imperial College London, London, UK.
Hepatic medicine : evidence and research
|November 15, 2023
概括
本综述详细介绍了SARS-CoV-2如何影响肝脏,包括那些患有肝脏疾病的人. 它还检查了COVID-19疫苗接种.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 病毒学 病毒学
- 免疫学 免疫学 免疫学
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 影响呼吸系统以外的器官,特别是肝脏.
- 了解肝脏对SARS-CoV-2的反应对于管理冠状病毒病19 (COVID-19) 患者至关重要.
研究的目的:
- 为了记录SARS-CoV-2对健康个体和已患有肝病的人的肝脏的影响.
- 为了检查COVID-19疫苗接种和肝损伤之间的关系.
- 探索SARS-CoV-2相关的肝损伤机制及其长期后果.
主要方法:
- 关于SARS-CoV-2和肝脏参与研究的综合文献综述.
- 对有关COVID-19对肝脏健康影响的临床数据和研究结果的分析.
- 探索导致肝损伤的免疫和病理机制.
主要成果:
- SARS-CoV-2 感染可以在健康人群和患有肝脏疾病的人群中引起肝损伤.
- 接种COVID-19疫苗和肝损伤之间的关系是复杂的,需要进一步调查.
- 特定的机制有助于SARS-CoV-2引起的肝损伤,并有可能导致长期的后果.
结论:
- SARS-CoV-2 对肝脏健康构成重大威胁,需要对所有患者进行仔细监测.
- 需要进一步的研究才能充分了解COVID-19疫苗接种对肝功能的影响.
- 长期跟踪对受COVID-19影响的患者至关重要,特别是那些有先前存在的肝病患者.
相关概念视频
Diseases of the Liver and Gallbladder
579
Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
579
Liver Physiology
585
The liver, an essential organ in the human body, performs over 200 vital functions that can be broadly categorized into metabolic, hematological, endocrine regulation, and bile production.
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...
585
Gross Anatomy of the Liver
474
The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is...
474
Pneumonia II: Pathophysiology
293
The pathophysiology of pneumonia involves the following steps:
293
Chronic Pancreatitis II: Collaborative Care
95
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
95
COPD: Pathogenesis and Clinical Features
302
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
302


