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Updated: Jul 11, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
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SpiB调节B细胞相关基因的表达,并增加记忆B细胞的寿命

Shu Horiuchi1, Takuya Koike1, Hirofumi Takebuchi1

  • 1Division of Cancer Cell Biology, Research Institute for Biomedical Sciences, Tokyo University of Science, Noda, Chiba, Japan.

Frontiers in immunology
|November 15, 2023
PubMed
概括

转录因子SpiB对于产生长期记忆B细胞至关重要,这对于适应性免疫是必不可少的. SpiB通过调节血细胞分化和促进生存基因来维持这些细胞.

关键词:
这就是SpiBB.在SpiB条件淘汰赛小鼠中使用.灭症 (apoptosis) 是一种死亡的过程.自自是自的过程.生殖中心 B 细胞的生殖中心幽默性免疫反应是一种免疫反应.记忆B细胞是一个B细胞.

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