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针对常规1型树突细胞的CAR-T细胞和CAR-Treg抑制实验性自身免疫脑膜炎

Cody D Moorman1, Sherman Yu1, Carlos G Briseno1

  • 1Amgen Research, Amgen Inc., South San Francisco, CA, United States.

Frontiers in immunology
|November 15, 2023
PubMed
概括

针对传统的1型树突细胞 (DC1) 与仿真抗原受体 (CAR) -T细胞或CAR-Tregs的向可以抑制自身免疫反应. 这种方法在实验性自身免疫性脑膜炎 (一种多发性硬化症模型) 中显示出适度的抑制作用.

关键词:
在CAR-T细胞中.这就是CAR-Treg.XCR1 是一个 XCR1 的类型.自身免疫性疾病是一种自身免疫性疾病.自体免疫性是一种自身免疫性.仿制性抗原受体的仿制性抗原受体1型常规树突细胞.

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