相关实验视频

Updated: Jul 11, 2025

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids

Establishment and Characterization of Small Bowel Neuroendocrine Tumor Spheroids

Published on: October 14, 2019

早期发病和晚期发病小肠腺癌之间的临床病理比较:一个多中心国际研究

Giovanni Arpa^1,2, Alessandro Vanoli², Francesca Antoci³

¹Unit of Anatomic Pathology, ICS Maugeri-IRCCS SpA SB, Pavia, Italy.

The American journal of gastroenterology

|November 15, 2023

概括

早期发病的小肠腺癌 (EO-SBA) 与诸如腹腔疾病之类的诱发性疾病有关. 在EO-SBA患者中,常规查胰腺疾病至关重要.

科学领域:

胃肠病学胃肠病学
在瘤学瘤学.
病理学病理学病理学

背景情况:

早期发生的小肠腺癌 (EO-SBA) 是一种罕见的疾病.
关于其临床病理学特征的数据有限.

研究的目的:

将EO-SBA的临床病理特征与晚发SBA进行比较.
在EO-SBA中识别风险因素和关联.

主要方法:

追溯国际多中心队列研究.
包括208名小肠腺癌 (SBA) 患者.
将50岁以下的患者 (EO-SBA) 与50岁以上的患者进行了比较.

主要成果:

在EO-SBA (P = 0.003) 中,易感性疾病更常见 (P = 0.003).
在EO-SBA组中,乳病的患病率显著更高.
患有先导性疾病的相对风险为1.50 (95% CI: 1.20-1.86).

结论:

EO-SBA与诱导性疾病,特别是乳病有着强烈的关联.
对于EO-SBA患者,建议进行常规的乳病查.

更多相关视频

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

A Genetically Engineered Mouse Model of Sporadic Colorectal Cancer

Published on: July 6, 2017

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Comparative Lesions Analysis Through a Targeted Sequencing Approach

Published on: November 5, 2019

相关概念视频

Tumor Progression

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...