在医院环境中共同循环的Omicron血统的实质性多样性,巴西波尔图阿莱格里,巴西
Emerging infectious diseases
|November 15, 2023
概括
巴西的SARS-CoV-2 Omicron变异多样性显示BQ.1和相关系系是最常见的. 在医疗工作者和住院患者中,也检测到了更新的血统BE.9.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 基因组监测 基因组监测
背景情况:
- SARS-CoV-2 Omicron 变种已迅速演变,导致具有明显流行病学特征的众多亚系.
- 了解SARS-CoV-2变种的遗传多样性和循环模式对于公共卫生干预至关重要.
研究的目的:
- 描述在巴西阿莱格里市流传的SARS-CoV-2 Omicron血统的遗传多样性.
- 为了确定占主导地位的血统及其在医疗保健工作者和住院患者中的流行率.
主要方法:
- 272个SARS-CoV-2阳性样本的全基因组测序.
- 遗传学分析以确定Omicron血统. 遗传学分析以确定Omicron血统.
- 对2022年11月至2023年1月期间采集的样本进行回顾性分析.
主要成果:
- 检测到23种SARS-CoV-2 Omicron血统的大量多样性.
- BQ.1及其相关系构成了大部分 (61.4%) 的测序样本.
- 在亚马逊地区首次发现的BE.9血统也被检测到 (19.1%).
结论:
- 该研究强调了巴西的SARS-CoV-2 Omicron变种多样性.
- BQ.1和BE.9代表重要的循环系,需要持续监测.
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