双主动脉疾病的长期结果
Julia Aschauer1, Robert Zilberszac1, Andreas Gleiss2
1Department of Cardiology, Vienna General Hospital, Medical University of Vienna, Waehringer Guertel 18-20, Vienna 1090, Austria.
European heart journal. Cardiovascular Imaging
|November 15, 2023
概括
双动脉 (BAV) 疾病有很多心脏事件,但良好的护理提供了生存. 大动脉狭窄,反,扩张和年龄预测这些事件.
科学领域:
- 心脏病学 心脏病学
- 遗传性心脏病是一种先天性心脏病.
- 大动脉膜疾病 大动脉膜疾病
背景情况:
- 双动脉 (BAV) 是一种常见的先天性心脏缺陷.
- BAV与大动脉狭窄 (AS),大动脉吐 (AR) 和大动脉动脉瘤有关.
- 对于BAV患者的具体结局数据有限.
研究的目的:
- 评估大量连续患有BAV.的患者队列中的临床结果.
- 为了确定BAV患者心脏事件的预测因素.
主要方法:
- 在心脏门诊所对581名连续BAV患者的潜在随访.
- 分析整体生存率和无事件生存率.
- 多变量分析以确定心脏事件的独立预测因素.
主要成果:
- 总体上,10年生存率为94.5%.
- 1,2,5年和10年的无事件生存率分别为97%,94%,87%和73%.
- 心脏事件的预测因素包括AS,AR,基线大动脉扩张 (≥40毫米),和年龄.
结论:
- BAV疾病与心脏事件的高发病率有关.
- 现代管理导致良好的存活率,内心炎,剖析和突然死亡的风险较低.
- AS和AR的严重程度,大动脉扩张和患者年龄是不良事件的关键预测因素.
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