为什么成年人接触液体洗衣剂囊?
Anna Celentano1, Maurizio Bissoli1, Fabrizio Sesana1
1Centro Antiveleni di Milano e Farmacologia Clinica, Azienda Socio Sanitaria Territoriale Niguarda, Milan, Italy.
Clinical toxicology (Philadelphia, Pa.)
|November 15, 2023
概括
在成年人中,液体洗衣剂囊暴露的研究不足. 摄入在患有痴呆症的成年人中最常见,有些人死亡,这突显了严重的公共卫生问题.
科学领域:
- 毒理学 毒理学 毒理学
- 公共卫生 公共卫生
- 老年病的医生 老年病的医生
背景情况:
- 在成年人中,液体洗衣剂囊 (LLDC) 的暴露程度比在儿童中了解得更少.
- 成年LLDC暴露数据对于有针对性的预防和治疗策略至关重要.
研究的目的:
- 描述成年人接触液体洗衣剂囊的情况.
- 确定与成人LLDC暴露相关的风险因素和结果.
主要方法:
- 对米兰毒药控制中心关于成人LLDC暴露的所有查询的分析 (2010年7月至2023年7月).
- 通过根据暴露严重程度的召回来跟踪患者.
- 收集了关于年龄,暴露途径和患者认知状态的数据.
主要成果:
- 记录了127个成年人的暴露,摄入是最常见的途径 (n=54).
- 在那些摄入囊的人中,63%患有痴呆症或认知障碍,在这小组中发生了三起死亡事件.
- 皮肤和眼部暴露不涉及患有痴呆症的人.
结论:
- 意大利的大多数成人LLDC摄入涉及患有痴呆症或认知障碍的人.
- 认知障碍是LLDC摄入后严重后果的重要风险因素,包括死亡.
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