相关实验视频
Updated: Jul 11, 2025

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Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
735
在恶性多叶半径瘤免疫治疗后进行救援性多叶切除术/脱皮术
Masaru Takenaka1, Koji Kuroda1, Katsuma Yoshimatsu1
1Second Department of Surgery (Chest Surgery), University of Occupational and Environmental Health, Kitakyushu, Japan.
Interdisciplinary cardiovascular and thoracic surgery
|November 15, 2023
概括
在免疫疗法后的救援手术显示出对晚期恶性多叶膜间皮瘤 (MPM) 的前景. 这种方法在所有病例中都实现了完全切除,没有手术死亡,这表明对某些患者的可行性.
科学领域:
- 在瘤学瘤学.
- 胸部外科手术 胸部外科手术
- 免疫治疗是一种免疫疗法.
背景情况:
- 恶性多层层层瘤 (MPM) 是一种具有攻击性的癌症.
- 免疫治疗后的救生手术是晚期瘤的新兴选择.
- 关于MPM免疫治疗后的救援手术的数据有限.
研究的目的:
- 评估最初无法切除的MPM免疫疗法后救援手术的可行性.
- 评估结果,包括切除能力,发病率和存活率.
主要方法:
- 追溯研究61名接受了多切除/脱皮术 (P/D) 的MPM患者.
- 七名患者在免疫治疗后接受了救援P / D,以转换到可切除性或局部复发.
- 宏观彻底切除是首要的手术目标.
主要成果:
- 所有7名患者都实现了宏观的完全切除.
- 救援P/D涉及更长的操作时间和更高的血液损失,但没有术后死亡率.
- 免疫治疗的放射性反应与病理反应相关.
- 随访时间中位数为9.0个月,大多数患者活着,没有复发.
结论:
- 免疫治疗后的救援P/D似乎是可行的,对于精选的高级MPM患者.
- 需要进一步的多机构研究和长期跟踪来确认临床益处.
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