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Updated: Jul 11, 2025

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

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响应p53的CMBL重编程葡萄糖代谢,并通过破坏酸果酶PFKP的稳定性来抑制癌症的发展

Yingdan Huang1, Chen Xiong2, Chunmeng Wang3

  • 1Fudan University Shanghai Cancer Center and Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China; Department of Lymphoma Medicine (Breast Cancer & Soft Tissue Tumor Medicine), Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430079, China.

Cell reports
|November 15, 2023
PubMed
概括

这种类似于碳基甲丁醇酶 (CMBL) 的蛋白质通过抑制糖解抑制结肠直肠癌 (CRC) 的生长. 由于CMBL缺乏,瘤对糖解抑制剂具有敏感性,这表明了新的治疗策略.

关键词:
在CMBL中,CMBL是指CMBL.CP: 癌症 癌症 癌症CP:新陈代谢过程中的新陈代谢.现在,我们可以看到PFKPPFKP.在 TRIM2525 中,癌症治疗疗法 癌症治疗结肠直肠癌是什么意思葡萄糖溶解是什么在 p53 里,p53 是一个 p53 的类型.

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