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Updated: Jul 11, 2025

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
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Published on: May 5, 2023

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ACD15,ACD21和SLN调节MBD6的积累和流动性,以使基因和可移植元素沉默

Brandon A Boone1,2, Lucia Ichino1,2, Shuya Wang1,2

  • 1Molecular Biology Institute, University of California Los Angeles, Los Angeles, CA 90095, USA.

Science advances
|November 15, 2023
PubMed
概括

新的蛋白质ACD15和ACD21是MBD5/6复合体的关键,驱动基因沉默,并在CG位点形成动态DNA甲基化组件.

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