性作为口腔疾病中的生物变量:证据和未来前景
L Sangalli1, L C Souza2, A Letra3
1College of Dental Medicine-Illinois, Midwestern University, Downers Grove, IL, USA.
Journal of dental research
|November 15, 2023
概括
性别和性别显著影响口腔健康和疾病. 本综述综合了口腔疾病中的性别差异,强调了需要个性化,基于性别的治疗策略的需要.
科学领域:
- 生物医学科学 生物医学科学
- 口腔健康研究研究 口腔健康研究
- 医学中的性别和性别.
背景情况:
- 在过去的25-30年中,对性别和性别健康差异的科学兴趣越来越大.
- 有证据表明,性别和性别影响分子,细胞和疾病过程.
- 对于理解健康差异和制定有针对性的干预措施至关重要.
研究的目的:
- 综合有关各种口腔疾病中性别差异的当前知识.
- 探索性别和性别对口腔健康和疾病倾向/进展的影响.
- 发现有关口腔健康的心理社会和外部因素的研究缺口.
主要方法:
- 覆盖范围审查方法.
- 综合来自人类和动物模型研究的证据.
- 分析口腔疾病,包括牙周病,牙损伤,口腔面部疼痛和牙周炎.
主要成果:
- 强有力的证据支持性二态性在口腔疾病的倾向和/或进展.
- 性别影响口腔疾病的风险,从牙损伤到顶端牙周炎.
- 在当前的研究中缺乏对性别和心理社会因素的考虑.
结论:
- 性是口腔疾病发展和进展的一个重要因素.
- 当前的研究往往忽略了关键的性别和心理社会影响.
- 需要为基于性别的个性化口腔保健策略开发新的框架.
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