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Author Spotlight: Genetic Profiling for Fluorouracil Response in Gastric Cancer
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柳科沃林和甲与或没有氧化作为先进结肠直肠癌的第一线治疗

A de Gramont1, A Figer1, M Seymour1

  • 1From the Service de Médecine Interne-OncologieHôpital Saint-Antoine, Paris; Debiopharm, Charenton; Service d'Oncologie Médicale, Centre Hospitalier Lyon Sud, Pierre-Benite; and Centre Hospitalier René Dubos, Pontoise, France; Institute of Oncology, Belinson Medical Center, Petach Tikva, Israel; Imperial Cancer Research Fund Cancer Medicine Research Unit, University of Leeds; Department of Medicine and Therapeutics, University of Aberdeen, Aberdeen; Department of Medical Oncology, St Bartholomew's Hospital, London; and Addenbrooke's National Health Service Trust, Cambridge, United Kingdom; Servizio di Oncologia Medica, Arcispedale S. Maria Nuova, Reggio Emilia; Instituto Europeo di Oncologia, Milan; and Clinical Oncology Centre, Service d'Oncologie Médicale, Div Oncologia Medica Azienda, Ospedaliera di Verona, Verona, Italy; Servicio de Oncología, the Hospital 12 de Octubre, Madrid; and Servicio de Onco-Hematologia, Hospital Clinico Universitario, Valencia, Spain.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology
|November 15, 2023
PubMed
概括

添加oxaliplatin到leucovorin (LV) 加上fluorouracil (5FU) 治疗方案显著改善了晚期结直肠癌患者的无进展生存率. 这种组合疗法显示出更好的反应率,并保持了生活质量,尽管毒性增加.

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