Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Antidepressant Drugs: MAOIs and Other Agents01:23

Antidepressant Drugs: MAOIs and Other Agents

248
Atypical antidepressants, including bupropion (Wellbutrin), mirtazapine (Remeron), nefazodone (Serzone), trazodone (Desyrel), and vilazodone (Viibryd), offer unique mechanisms of action. Bupropion weakly inhibits dopamine and norepinephrine reuptake, aiding depression treatment and smoking cessation, with a low risk of sexual dysfunction. Mirtazapine enhances serotonin and norepinephrine neurotransmission, leading to sedation, increased appetite, and weight gain. As a result, it helps treat...
248
Electroconvulsive Therapy01:30

Electroconvulsive Therapy

44
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
44
Treatment Strategies for Psychological Disorders01:24

Treatment Strategies for Psychological Disorders

138
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
138
Comparing the Survival Analysis of Two or More Groups01:20

Comparing the Survival Analysis of Two or More Groups

199
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
199
Cognitive Therapy01:25

Cognitive Therapy

153
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
153
Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs01:28

Antidepressant Drugs: Tricyclics, SSRIs, and SNRIs

403
Tricyclic Antidepressants (TCAs), including Desipramine (Norpramin), Imipramine (Tofranil), Clomipramine (Anafranil), and Amitriptyline (Elavil), inhibit serotonin and norepinephrine reuptake and also block other receptors. They are used for depression, pain conditions, and insomnia. Common adverse effects include anticholinergic effects, sedation, orthostatic hypotension, and weight gain. They have a narrow therapeutic window and so require plasma-level monitoring. Abrupt discontinuation can...
403

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Discussing sexuality, contraception, family planning, pregnancy and parenthood in mental healthcare.

Journal of reproductive and infant psychology·2026
Same author

A temporal network analysis of drug co-prescription during antidepressants and anxiolytics dispensing in the Netherlands from 2018 to 2022.

Global epidemiology·2026
Same author

A National Survey of Adherence to Glucose-Lowering Medication Among Adults With Diabetes in Indonesia.

Tropical medicine & international health : TM & IH·2025
Same author

Modeling effect: How treatment intensity and duration impact depression recurrence.

European psychiatry : the journal of the Association of European Psychiatrists·2025
Same author

Associations between childhood maltreatment, PTSD and metabolic outcomes in patients with common mental disorders at outpatient clinics in specialized care.

BMC psychiatry·2025
Same author

Psychometric properties of the treatment satisfaction with medicine questionnaire (SATMED-Q) in Indonesian patients with type 2 diabetes.

The International journal of pharmacy practice·2025

相关实验视频

Updated: Jul 11, 2025

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

28.6K

对算法引导治疗和预定义持续时间的抑郁症治疗计划进行比较分析:利用例行护理数据探索成本效益.

Fang Li1, Ellen Visser2, Maarten Brilman2

  • 1University of Groningen, Faculty of Science and Engineering, Groningen Research Institute of Pharmacy, Groningen, The Netherlands f.li@rug.nl.

BMJ mental health
|November 15, 2023
PubMed
概括

算法引导的抑郁症治疗产生了更大的健康益处,但更昂贵,在当前的门下证明不具有成本效益. 这项研究有助于决策者优化治疗分配和提高护理质量.

关键词:
抑郁症和情绪障碍 抑郁症和情绪障碍

更多相关视频

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.6K
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

13.9K

相关实验视频

Last Updated: Jul 11, 2025

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
04:29

Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

Published on: January 7, 2019

28.6K
Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

3.6K
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
08:20

MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder

Published on: August 11, 2015

13.9K

科学领域:

  • 卫生经济学 卫生经济学
  • 心理健康服务研究 心理健康服务研究
  • 临床决策 临床决策

背景情况:

  • 成本效益数据对于有效的抑郁症治疗分配和改善护理质量至关重要.
  • 了解不同抑郁症管理策略的经济影响至关重要.

研究的目的:

  • 为了比较两个抑郁症治疗方案的实际成本效益:以算法为指导的缓解为重点,与以患者偏好为中心的响应为重点.
  • 从医疗保健系统的角度来看,使用例行护理数据来评估这些计划.

主要方法:

  • 一项涉及6295名参与者的自然主义研究在两年内进行.
  • 以质量调整的生命年 (QALY) 和无抑郁日 (DFD) 被用作结果指标.
  • 计算了增量成本效益比率 (ICER),通过引导和灵敏度分析评估不确定性.

主要成果:

  • 算法引导的程序导致了更多的DFD (12) 和QALY (0.013),但成本更高 (3070欧元).
  • ICER大约为256欧元/DFD和236154欧元/QALY,这表明与预先定义的持续时间计划相比,成本效益较低.
  • 算法引导的程序在5万欧元/QALY值时具有<10%的成本效益概率;灵敏度分析证实了这些发现.

结论:

  • 虽然算法引导的程序取得了更大的健康收益,但其较高的成本使其在当前荷兰经济门内不具有成本效益.
  • 这两种治疗方案都有不同的好处,取决于患者的偏好和医疗预算.
  • 这项研究为优化治疗分配和提高抑郁症护理成本效益提供了宝贵的见解.