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Updated: Jul 11, 2025

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在CAR-T治疗中构建安全性

Daniel T Peters1, Barbara Savoldo2, Natalie S Grover3

  • 1Department of Hematology Oncology, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

Human vaccines & immunotherapeutics
|November 15, 2023
PubMed
概括

化学抗原受体T细胞 (CAR-T) 疗法对血液癌症有希望,但会导致毒性. 新的安全措施至关重要,特别是在固体瘤应用中,可诱导的Caspase 9提供了一个潜在的解决方案.

关键词:
在CART-T中,我们可以使用CAR-T.在CRS中,您可以使用CRS.在ICANS中,我们可以看到ICANS.细胞疗法是细胞疗法.可诱导的卡斯巴酶9安全开关的安全开关

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