在患有基本高血压的儿童中,左心室缩和重新建模:种族是否重要?
Daiji Takajo1, Thomas S Przybycien2, Preetha L Balakrishnan2
1Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI, USA.
Cardiology in the young
|November 15, 2023
概括
肥胖,而不是种族,与患有基本高血压的儿童的左心室缩有关. 这项研究没有发现左心室缩患病率存在显著的种族差异,但确定了超重/肥胖是关键预测因素.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 高血压研究 高血压研究
- 心血管成像 - 心血管成像
背景情况:
- 儿童的基本高血压是一个日益关注的问题.
- 对心脏结构的回声心脏学评估对于了解高血压相关并发症至关重要.
- 以前的研究还没有完全阐明种族在儿科高血压引起的心脏变化中的作用.
研究的目的:
- 调查种族对心声图左心室缩和适应新诊断患有基本高血压的儿童的种族影响.
- 为了比较非洲裔美国人和高加索儿童之间的左心室缩和相对壁厚的患病率.
- 在这个儿科群体中确定左心室缩的预测因子.
主要方法:
- 一项对422名新诊断的基本高血压儿童 (年龄在3-18岁) 的横截面研究.
- 心声学被用来测量左心室质量指数和相对壁厚度.
- 左心室缩定义为LVMI>95百分位;同心适应作为RWT>0.42.
主要成果:
- 在非洲裔美国人 (22.5%) 和白人 (17.3%) 之间,左心室缩患病率没有统计学上显著的差异.
- 非洲裔美国人显示左心室相对壁厚度增加的患病率显著更高 (30.1%对20.3%,p=0.04).
- 超重/肥胖强烈预测左心室质量指数升高,而非裔美国人种族预测相对壁壁厚度增加.
结论:
- 种族对患有基本高血压的儿童左心室缩的患病率没有影响.
- 肥胖是左心室缩的一个显著预测因素,独立于种族.
- 增加左心室相对壁厚在非洲裔美国儿童中更为普遍,这表明心脏重塑模式可能存在种族差异.
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