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Updated: Jul 11, 2025

Identification of Skeletal Muscle Satellite Cells by Immunofluorescence with Pax7 and Laminin Antibodies
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PAX3-FOXO1在内皮细胞前代体中决定了肌原性重编程和狂宫肌肉瘤身份

Madeline B Searcy1,2, Randolph K Larsen1,2, Bradley T Stevens1,2

  • 1Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA.

Nature communications
|November 15, 2023
PubMed
概括

融合阳性狂肌肉瘤 (FP-RMS) 起源于非肌肉细胞. PAX3-FOXO1 (P3F) 基蛋白重编程内皮原生细胞成为FP-RMS,揭示了这种侵袭性儿科癌症的新型细胞起源.

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