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Updated: Jul 11, 2025

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用可编程生成模型照亮蛋白质空间

John B Ingraham1, Max Baranov1, Zak Costello1

  • 1Generate Biomedicines, Somerville, MA, USA.

Nature
|November 15, 2023
PubMed
概括

克罗玛是一种新的生成模型,通过采样新的结构和序列来设计新型蛋白质和蛋白质复合体. 实验验证表明设计的蛋白质具有功能,表达良好,并正确折叠.

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