怀孕期间经历歧视和同化对后代大脑发育的影响
Marisa N Spann1,2, Kiarra Alleyne3, Cristin M Holland4
1Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, USA. mns2125@cumc.columbia.edu.
概括
母亲的歧视和同化经历会影响婴儿的大脑连接. 歧视与杏仁体连接性变化有关,这表明对神经发育的代际影响.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 公共卫生 公共卫生
背景情况:
- 种族,种族和结构不平等会对健康产生负面影响.
- 怀孕期间母亲的经历可能会影响胎儿的发育.
- 关于歧视和融入文化如何影响婴儿大脑连接的研究有限.
研究的目的:
- 在怀孕的西班牙裔青少年中描述歧视和融入文化的经历.
- 评估这些体验与新生儿大脑功能连接之间的关联.
- 探索母亲心理社会因素对婴儿神经发育的潜在代际影响.
主要方法:
- 收集了165名孕妇关于适应文化,歧视,孕产妇痛苦和社会经济地位的自我报告数据.
- 利用数据驱动的聚类来识别不同的母亲表型.
- 分析了休息状态的功能性MRI数据,以评估38名新生儿的婴儿桃体连接性.
主要成果:
- 歧视和融入文化的风格形成了与母亲的痛苦和社会经济地位分开的独特因素.
- 较高的母体同化与较弱的新生儿桃体-双边状环连接性有关.
- 孕产妇的歧视与新生儿桃体与前额皮质和状环的连接性发生变化有关.
结论:
- 母亲的歧视和同化经历是影响新生儿大脑连接的明显的心理社会因素.
- 研究结果表明,歧视和同化对杏仁体电路的潜在代际影响.
- 需要对不同人群进行进一步的研究和全面的评估来确认这些关联.
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