在安得拉邦眼病研究 (APEDS) 中,初级开放角眼光病的发生率
Nikhil S Choudhari1,2, Rohit C Khanna3,4,5,6, Srinivas Marmamula2,7,8
1VST Glaucoma Centre, Dr. Kallam Anji Reddy Campus, L V Prasad Eye Institute, Banjara Hills, Hyderabad, India.
Eye (London, England)
|November 16, 2023
概括
印度农村地区15年间初级开放角眼镜瘤 (POAG) 的发病率为每100人年2.83. 发现的一种新风险因素是随着年龄的增长,眼内压力 (IOP) 的降低不那么明显.
科学领域:
- 眼科医生 眼科 眼科
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 安得拉邦眼病研究 (APEDS) 的目的是确定15年的初级开放角光眼瘤 (POAG) 发病率.
- 以前的研究还没有完全阐明印度农村人口中POAG的长期发病率.
研究的目的:
- 报告一个印度农村群体中15年初级开角眼光病 (POAG) 的发病率.
- 在15年的时间内确定与POAG发展相关的风险因素.
主要方法:
- 一项基于人口的纵向研究在基线和15年随访时进行,参与者在基线时年龄≥40岁.
- 进行了眼科检查,并使用ISGEO分类来定义玻璃眼.
- 在基线没有青光眼的参与者中计算了POAG的发病率.
主要成果:
- 在1241名符合条件的参与者中,POAG的15年发病率为每100人年2.83 (95% CI:2.6,3.08).
- 36名参与者患有POAG,其中17例是双边的.
- 随着年龄的增长,平均眼内压 (IOP) 的明显下降被确定为一个显著的危险因素.
结论:
- 这项研究提供了关于印度农村POAG发病率的关键长期数据.
- 内血压的纵向变化,特别是随着年龄的增长而导致内血压的减弱,代表了POAG.新型风险因素.
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