患有急性淋巴细胞白血病的儿童症状的发生率:系统性审查和元分析
Xiaoyan Lan1, Junjun Wu1, Zhenling Liao1
1School of Nursing, Fujian Medical University, No. 1 Xueyuan Road, Shangjie Town, Minhou County, Fuzhou, 350108, Fujian Province, China.
BMC cancer
|November 16, 2023
概括
在治疗期间,患有急性淋巴细胞白血病 (ALL) 的儿童经常出现症状. 疲劳,缺乏能量和口腔干燥是最常见的,突出了需要更好的症状管理策略.
科学领域:
- 儿科瘤学 儿科瘤学
- 血液学 血液学 血液学
- 症状管理 症状管理
背景情况:
- 患有急性淋巴细胞白血病 (ALL) 的儿童经历复杂的症状模式,影响结果.
- 没有先前的系统审查全面评估了儿科ALL的症状患病率.
研究的目的:
- 系统地审查和分析接受ALL治疗的儿童所经历的症状的患病率.
主要方法:
- 从2000年1月到2023年8月,对八个主要数据库进行了系统搜索.
- 评估了包括17项研究的方法质量.
- 进行了元分析,以确定综合症状流行率.
主要成果:
- 在17项研究中,在儿科ALL患者中发现了34种不同的症状.
- 症状的发病率范围广泛,从1.5%到91.0%.
- 最常见的症状包括疲劳,缺乏能量,口腔干燥,食欲不佳,出汗和易怒 (60%以上的患病率).
结论:
- 儿童ALL患者的症状非常普遍,这强调了常规临床症状评估的必要性.
- 需要紧急开发和实施有针对性的干预措施,以减轻ALL儿童的症状负担.
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