饮食碳水化合物和肝脂肪类型和来源之间的关联:英国生物银行的一项研究
Josefina Orliacq1,2, Aurora Pérez-Cornago2, Siôn A Parry3,4
1Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.
食纤维,非自由糖和全谷物粉摄入量与较低的肝脂肪有关,可能有助于预防与代谢功能障碍相关的脂肪性肝病 (MASLD). 精制谷物和自由糖与肝脏脂肪的关联不那么明显或积极.
科学领域:
- 营养科学 营养科学
- 肝病学 肝病学是一种肝病学.
- 代谢健康 代谢健康
背景情况:
- 过多的能量摄入有助于代谢功能障碍相关的脂肪性肝病 (MASLD).
- 饮食中的碳水化合物类型和来源对肝脏脂肪积累的具体影响尚未完全理解.
研究的目的:
- 调查各种食碳水化合物类型和来源与肝脏脂肪含量之间的联系.
- 为了区分不同碳水化合物成分对肝脏肥胖症的影响.
主要方法:
- 利用了来自没有先前存在条件的参与者的英国生物库数据.
- 采用了使用逻辑回归和前性分析 (n=9268) 的横截面分析 (n=22,973) 和用MRI测量肝脂肪 (PDFF) 的前性分析.
- 调整以人口统计,生活方式和总能量摄入量为混因素.
主要成果:
- 在肝脏脂肪和摄入纤维,非自由糖和全谷物粉之间发现了不良关联.
- 在肝脂肪和精制谷物粉摄入量之间观察到积极的关联.
- 自由糖摄入量在横截面分析中没有显著的关联,但在前性分析中与PDFF有积极的关联.
结论:
- 不同的碳水化合物来源与肝脏脂肪含量有不同的关系.
- 纤维,非自由糖和全谷物粉可能会对MASLD产生保护作用.
- 需要进一步的研究来澄清自由糖和精制谷物粉在肝脏脂肪积累中的作用.
更多相关视频
08:04Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
Published on: October 23, 2018
10:29Measuring Oral Fatty Acid Thresholds, Fat Perception, Fatty Food Liking, and Papillae Density in Humans
Published on: June 4, 2014
相关概念视频
Carbohydrates: Dietary Sources and Requirements
Overview of Carbohydrate Metabolism
Glucose transport into cells is facilitated by a family of transport proteins called GLUT (Glucose Transporters). GLUT4 is the primary glucose transporter for insulin-stimulated glucose...
Blood Studies for Cardiovascular System III: Serum Lipid Profile
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Lipids: Dietary Sources and Requirements
Overview of Lipid Metabolism
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
