败血症住院后恢复工作:全国范围的基于登记册的队列研究
Nina Vibeche Skei1,2, Karoline Moe3, Tom Ivar Lund Nilsen3
1Department of Intensive Care and Anesthesia, Nord-Trondelag Hospital Trust, Levanger, Norway. nina.v.skei@ntnu.no.
Critical care (London, England)
|November 16, 2023
概括
败血症住院后恢复工作 (RTW) 仍然具有挑战性,病例率稳定,但非ICU患者的病率下降. 可持续的RTW与年轻的年龄和较少的并发症有关,突显了改善患者治疗结果的必要性.
科学领域:
- 临界护理医学 临界护理医学
- 公共卫生 公共卫生
- 职业健康 职业健康 职业健康
背景情况:
- 败血症幸存者经常经历功能障碍,影响他们恢复工作的能力.
- 对于了解长期康复和社会重返来说,研究败血症幸存者的重返工作 (RTW) 和相关因素至关重要.
研究的目的:
- 研究在工作年龄的败血症幸存者中恢复工作 (RTW) 的比例和可持续性.
- 探索患者特征,临床因素和RTW结果之间的关联.
- 分析十年来RTW比例的时间趋势.
主要方法:
- 一项使用2010-2021年挪威登记处 (患者登记处,国家社会保障系统) 的队列研究.
- 包括因败血症住院的劳动年龄 (18-60岁) 患者.
- 结果包括6个月,1年和2年的RTW,时间趋势以及使用时间到事件分析的可持续RTW的概率.
主要成果:
- 在35,839例败血症住院病例中,分析了12,260名 (34.2%) 工作患者.
- 在6个月,1年和2年的RTW率分别为58.6%,67.5%和63.4%.
- 可持续的RTW与年轻的年龄,较少的并发症和较少的器官功能障碍有关;ICU患者的概率较低 (HR 0.56) 和COVID-19败血症患者的概率较高 (HR 1.31) 相比,非ICU和非COVID-19败血症患者的概率分别较低. 观察到非ICU患者的2年RTW下降.
结论:
- 随着时间的推移,回归工作 (RTW) 的比例没有得到改善,可持续的RTW仍然是败血症幸存者的担忧.
- 需要进一步的研究来确定可以增强功能恢复和改善败血症患者的RTW结果的干预措施.
- 特定的患者子组,例如需要接受ICU治疗的严重疾病患者,在恢复工作方面面临更大的挑战.
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