微提取与智能手机检测烟草吸烟者的唾液中的硫酸盐,使用纸质分析方法
1Department of Chemistry, College of Science, Salahaddin University, Erbil, Kurdistan Region, Iraq.
Journal of separation science
|November 16, 2023
概括
这项研究引入了一种成本效益高的方法,使用光谱光度和智能手机基于纸张的分析来测量唾液中的硫酸盐. 这种新的方法为潜在的健康监测提供了准确的量化.
科学领域:
- 分析化学 分析化学
- 环境科学 环境科学
- 生物医学诊断 生物医学诊断
背景情况:
- 氨酸是唾液中发现的一种生物标志物.
- 需要准确和可访问的量化方法来进行硫酸酸盐分析.
- 现有的方法可能昂贵或复杂.
研究的目的:
- 开发和验证一种新的,具有成本效益的方法来定量唾液中的硫酸盐.
- 使用光谱光度和智能手机纸质 (SPB) 技术.
- 采用一种空气辅助的分散微提取方法.
主要方法:
- 基于其对爱默生反应 (金胺染料形成) 的抑制作用的酸的量化.
- 通过监测色彩强度减弱,在525nm的光谱光度检测.
- 智能手机基于纸张 (SPB) 分析,使用智能手机捕获的颜色组件分析 (RGB).
主要成果:
- 光谱光度和SPB方法都显示出良好的线性 (10-100μg/L).
- 检测极限为7.5μg/L (光谱测量) 和8.8μg/L (SPB). 检测极限为7.5μg/L (光谱测量) 和8.8μg/L (SPB). 检测极限为7.5μg/L (光谱测量) 和8.8μg/L (SPB). 检测极限为7.5μg/L (光谱测量) 和8.8μg/L (SPB).
- 实现了高缩系数 (46%) 和提取回收 (93%).
结论:
- 开发的方法准确地量化了唾液样本中的硫酸盐.
- 这种方法具有成本效益,并利用可访问的技术 (智能手机).
- 结果与经过验证的方法可比,表明临床效用.
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