有活性的恶性瘤的孕妇患有静脉血栓栓塞的风险:系统性审查和元分析
Sara Folkins1, Ashley Miller2, Christopher M Nash3
1Dalhousie University Medical School, Halifax, Nova Scotia, Canada.
Acta obstetricia et gynecologica Scandinavica
|November 16, 2023
概括
患有活跃癌症的孕妇面临着明显更高的静脉血栓塞栓症 (VTE) 风险. 这一系统性审查强调了恶性瘤怀孕中VTE几率的增加,表明需要更密切的监测和潜在的预防性抗凝药.
科学领域:
- 产科和妇科 产科和妇科
- 血液学 血液学 血液学
- 在瘤学瘤学.
背景情况:
- 怀孕和活跃的恶性瘤是静脉血栓塞栓症 (VTE) 的独立危险因素.
- 大约每1000例怀孕中就有1例患有癌症.
- 这项研究系统地审查了活跃恶性瘤的孕妇患者与没有活跃恶性瘤的孕妇患者的静脉瘤发病率.
结论:
- 怀有活跃恶性瘤的怀孕与单独怀孕相比,增加了相当大的VTE风险.
- 在怀孕期间和分娩后,预防性抗凝药可能对这种高危人群是有必要的.
- 由于数据有限,需要进行进一步的研究,以提供基于癌症类型的具体建议.
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