在转移性骨病的关节整形术后使用阿片类药物
Gayathri Vijayakumar1, Dylan Vance2, Matthew W Colman3
1Department of Orthopedic Surgery, Section of Orthopedic Oncology, Rush University Medical Center, Chicago, Illinois. ORCID: https://orcid.org/0000-0001-7324-4864.
Journal of opioid management
|November 16, 2023
概括
这项研究发现,经过全关节整形手术 (THA) 的转移性骨病 (MBD) 患者的术后阿片类药物使用量减少. 90天后的阿片类药物使用与早期的术后使用有关.
科学领域:
- 整形外科手术 整形外科手术
- 在瘤学瘤学.
- 疼痛管理 疼痛管理
背景情况:
- 转移性骨病 (MBD) 经常影响部,往往需要全关节整形术 (THA) 来缓解疼痛和改善功能.
- 后THA疼痛管理通常涉及短期阿片类药物处方.
- 没有先前的研究专门检查了在THA后的阿片类药物使用模式在MBD患者中.
研究的目的:
- 评估手术后的阿片类药物消费在THA后的MBD患者.
- 在手术后6周和90天确定阿片类药物使用的预测因素.
主要方法:
- 对手术前服用阿片类药物并接受初级THA的MBD患者的回顾性审查.
- 在手术后6周和90天的阿片类药物使用量化 (吗啡毫克相当量 - - MMEs).
- 术前和术后MME的统计比较以及与持续使用阿片类药物相关的因素分析.
主要成果:
- 高比例的患者在THA.后6周 (86.7%) 和90天 (76.7%) 继续使用阿片类药物.
- 从术前水平到术后90天,观察到每日MME的统计显著下降 (p < 0.001).
- 6周的阿片类药物使用是90天阿片类药物使用的唯一显著预测因素.
结论:
- 这项研究是首次报告手术后的阿片类药物使用后的THA在MBD患者.
- 在MBD的背景下,THA似乎与手术后阿片类药物需求的减少有关,尽管仍然普遍存在.
- 建议进行更大规模的队列研究,以进一步阐明在MBD中关节关节整形术后的阿片类药物使用模式.
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