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素诱导的大脑微血管稀缺预测了代谢性疾病中抑郁症状的出现

Brayden D Halvorson1, Yuki Bao2, Krishna K Singh1

  • 1Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada.

Journal of applied physiology (Bethesda, Md. : 1985)
|November 16, 2023
PubMed
概括

代谢性疾病导致大脑微血管稀缺,与肥胖大鼠的抑郁症状有关. 阻断血栓素A2 (TxA2) 减少了这些影响,这表明血管和情绪障碍的治疗点.

关键词:
大脑血管病变大脑血管病变认知障碍 认知障碍是一种认知障碍.微血管功能障碍 微血管功能障碍肥胖和胰岛素耐药性 肥胖和胰岛素耐药性代谢性疾病的动物模型.

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