患有严重冠状病毒病的患者中的巴罗创伤2019年回顾性观察研究
Petra Bajto1, Ivana Saric1, Josipa Domazet Bugarin1
1Department of Anesthesiology, Reanimatology and Intensive Care, University Hospital Split, Split, Croatia.
Journal of thoracic disease
|November 16, 2023
概括
9.8%的COVID-19患者患有肺气质创伤,需要重症监护室 (ICU) 的支持. 这种并发症与严重的COVID-19病例的生存率降低和更长的住院时间有关.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 严重急性呼吸系统综合征冠状病毒2 (SARS-CoV-2) 导致COVID-19,通常导致急性呼吸系统应急综合征 (ARDS).
- 肺重创是COVID-19 ARDS中已知的并发症,但其具体机制需要进一步调查.
- 了解COVID-19患者的重创发病率和结果对于改善患者管理至关重要.
研究的目的:
- 为了确定COVID-19的重症监护室 (ICU) 患者中肺巴罗创伤的发生率.
- 在这个患者群体中分析与巴罗创伤相关的临床结果.
主要方法:
- 对接受ICU治疗的成年COVID-19患者进行了回顾性观察队列研究.
- 患者接受了侵入性呼吸系统支持,并根据肺部巴罗创伤的发生进行分类.
- 数据从2020年9月1日至2022年2月28日期间的电子医疗记录中收集.
主要成果:
- 在900名符合条件的COVID-19重症监护病房患者中,9.8%的患者观察到肺腹筋创伤.
- 常见的重创症状包括皮下肺 (83%),肺中 (77.3%) 和肺胸 (61.4%).
- 与对照组相比,巴罗创伤组的生存率明显较低 (25.0%vs48.8%),ICU/住院停留时间较长.
结论:
- 在需要呼吸支的严重COVID-19患者中,巴罗创伤的发展与较差的结果相关,包括生存率降低和长时间住院治疗.
- 进一步的研究对于阐明COVID-19中巴罗创伤背后的机制至关重要.
- 在COVID-19患者中确定巴罗创伤的新型预防和治疗策略是一个至关重要的未满足的需求.
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