CT冠状动脉化得分作为COVID-19的预后标记
Hans-Jonas Meyer1, Sebastian Gottschling2, Jan Borggrefe3
1Department of Diagnostic and Interventional Radiology, University of Leipzig, Leipzig, Germany.
Journal of thoracic disease
|November 16, 2023
概括
在CT扫描上冠状动脉化 (CA) 评分是COVID-19患者死亡的独立风险因素. 较高的CA分数表明死亡风险更高,表明其在患者预后中的有用性.
科学领域:
- 心脏病学 心脏病学
- 放射学 放射学是一门学科.
- 传染性疾病 传染性疾病
背景情况:
- 冠状动脉化 (CA) 是动脉样硬化和心血管风险的公认生物标志物.
- 冠状动脉评分是冠状动脉疾病和其他疾病的确定的预后因素.
- 在2019年冠状病毒病 (COVID-19) 中CA的预后价值还没有完全阐明.
研究的目的:
- 研究冠状动脉化 (CA) 的预后相关性,使用计算机断层扫描 (CT) 在被诊断为COVID-19的患者中进行成像.
- 为了确定CA评分是否可以作为COVID-19患者死亡率的预测标记.
主要方法:
- 在2020年至2022年期间对COVID-19患者的临床数据库进行回顾性查.
- 在分析中包括241名COVID-19患者 (85名女性).
- 在使用韦斯顿分数的胸部CT图像上进行的半定量CA评分.
主要成果:
- 在研究期间,共有61名患者 (25.3%) 死亡.
- 与幸存者 (2.3±3.0) (P=0.002) 相比,没有幸存者的CA平均得分 (4.2±4.1) 显著更高 (P=0.002).
- 单变量和多变量回归分析证实,CA得分独立预测了COVID-19患者的30天死亡率 (OR=1.28,P=0.002).
结论:
- 冠状动脉化 (CA) 评分是COVID-19患者死亡的独立风险因素.
- 放射科医生轻松执行CA评分表明其作为一种有价值的成像标记物的潜力.
- 建议进一步调查并将CA评分转化为COVID-19患者管理的临床常规.
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