左侧的睡眠位置与改善胃食道逆流症症状有关:系统性审查和元分析
Daniel Martin Simadibrata1,2,3, Elvira Lesmana1, Bagus Ramasha Amangku1
1Department of Internal Medicine, Faculty of Medicine Universitas Indonesia, Jakarta 10430, Indonesia.
在左侧睡觉可以减少夜间酸性反流并改善GERD患者的生活质量. 建议使用这种姿势来控制胃食道逆流病的症状.
科学领域:
- 胃肠病学 胃肠病学
- 睡眠医学 睡眠医学
- 临床研究 临床研究
背景情况:
- 胃食道逆流性疾病 (GERD) 是一种常见的疾病,其特点是胃酸流回食道.
- 夜间反流发作可以显著影响患者的生活质量.
- 之前的研究表明,左侧 (LLD) 睡眠位置可能会减少GERD症状.
研究的目的:
- 系统地审查在患有GERD的患者中睡在LLD位置和夜间反流之间的关联.
- 评估LLD睡眠对关键GERD指标的影响.
主要方法:
- 从MEDLINE,EMBASE和CENTRAL获得的随机和非随机研究的系统审查,截至2023年7月17日.
- 对比LLD睡眠位置与右侧 (RLD) 和卧卧姿势.
- 评估结果,包括酸暴露时间 (AET),酸清除时间 (ACT),反流病例数和GERD症状影响问卷 (N-GSSIQ) 评分.
主要成果:
- 两项非随机研究表明,与RLD和卧卧相比,LLD位置的AET和ACT降低了.
- 在RLD和仰卧位置之间没有观察到AET或ACT的显著差异.
- 一项使用电子定位疗法增加LLD睡眠的随机对照试验显示,改善了夜间症状和无反流夜.
结论:
- 有证据表明,睡在LLD位置可以减少夜间反流.
- 该LLD职位可能会改善与GERD相关的生活质量.
- 促进LLD睡眠姿势的干预措施是GERD管理的必要条件.
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