在成年人患有肺动脉动脉和完整的心室隔膜的肺动脉动脉动脉功能障碍的预后影响
Alexander C Egbe1, William R Miranda1, Heidi M Connolly1
1Department of Cardiovascular Medicine, Mayo Clinic Rochester, Rochester, Minnesota, USA.
CJC pediatric and congenital heart disease
|November 16, 2023
概括
右心房 (RA) 应变成像是可行的,并预测肺动脉缩患者的结果. 在这种人群中,RA功能障碍很常见,与功能障碍,心律失常和死亡率有关.
科学领域:
- 心脏病学 心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 有完整腹腔隔膜的肺动脉缩 (PAIVS) 具有显著的发病和死亡风险.
- 对于PAIVS患者有效的风险分层存在有限的数据.
- 右心房 (RA) 功能至关重要,但在这个人群中研究不足.
研究的目的:
- 为了评估RA菌株指数的预后价值在PAIVS后双心脏修复的成年人中.
- 确定RA菌株是否可以帮助对不良临床结果的风险分层.
主要方法:
- 成年PAIVS患者 (2003-2019) 的回顾性分析与双心室修复.
- 心声学评估了RA储菌株;RA功能障碍定义为<31%的菌株.
- 临床结果包括功能障碍,肝功能障碍,心律失常/住院治疗,移植/死亡.
主要成果:
- 在43名患者中有95%的RA菌株成像是可行的;95%的患者表现出RA功能障碍.
- 副作用的高患病率:67%的功能障碍,49%的肝功能障碍,44%的心律失常/住院治疗.
- RA储菌株独立预测了所有评估的临床结果.
结论:
- 对于PAIVS患者的风险分层来说,RA菌株成像是可行的和有价值的.
- 关节炎功能障碍非常普遍,并与预后不佳有关.
- 需要对肝功能障碍和RA功能引导治疗进行进一步的研究.
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