乳腺癌治疗期间的体力活动与保持运动能力和心脏功能有关 (WF97415)
Moriah P Bellissimo1, Justin M Canada1, Jennifer H Jordan1,2
1Department of Internal Medicine, Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University School of Medicine, Richmond, Virginia, USA.
JACC. CardioOncology
|November 16, 2023
概括
乳腺癌 (BC) 治疗期间身体活动 (PA) 减少,但维持PA与更好的运动能力和心脏功能有关. 遵守PA指导方针可以预防BC患者的不良变化.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 运动生理学 运动生理学
背景情况:
- 癌症治疗可以提高心血管疾病的风险.
- 身体活动 (PA) 可以作为预防心血管疾病的保护因素.
研究的目的:
- 研究正在接受治疗的乳腺癌 (BC) 患者的休时间体育活动 (LTPA) 和次最大运动能力和心脏功能之间的关联.
- 为了确定更大的PA是否与癌症治疗期间保持心脏功能和运动能力有关.
主要方法:
- 在治疗前和治疗后3个月,评估了223名患有I-III期乳腺癌 (BC) 的妇女和126名对照.
- 休时间PA (LTPA) 使用戈丁-谢德LTPA问卷进行测量.
- 用心磁共振和6分钟步行测试分别评估心脏功能 (左心室周围应变) 和亚最大运动能力 (6分钟步行距离).
主要成果:
- 与对照组不同的是,BC患者在治疗期间显示LTPA的下降.
- 在BC患者中较高的LTPA与更好的运动能力和左心室 (LV) 周围应变相关.
- 不足的LTPA与运动能力,LV末缩体积,LV射出分数和LV周围应变的显著恶化有关.
结论:
- 身体活动 (PA) 水平在乳腺癌 (BC) 治疗期间下降.
- 在BC患者中,PA参与与运动能力和心脏功能减弱的下降有关.
- 满足PA指导方针可以减轻癌症治疗期间的不良心血管变化.
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