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鉴定腹腔镜彻底切除术后结直肠癌复发的多种风险因素

Jun Luo¹, Mei-Wen He¹, Ting Luo²

¹Department of Gastrointestinal Surgery, Peking University Shenzhen Hospital, Shenzhen 518036, Guangdong Province, China.

World journal of gastrointestinal surgery

|November 16, 2023

概括

确定手术后结直肠癌 (CRC) 复发的危险因素至关重要. 低分化,淋巴侵袭和像VEGF这样的特定血清标志物是CRC复发后拉皮镜切除的关键指标.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
胃肠病学胃肠病学

背景情况:

大肠直肠癌 (CRC) 需要手术干预,通常是腹腔镜彻底切除.
疾病复发仍然是一个重大的挑战,尽管成功的外科手术结果.
识别CRC复发风险因素对于改善患者管理和生存率至关重要.

研究的目的:

调查和确定与结直肠癌复发相关的危险因素.
分析 CRC 的腹腔镜激素切除后疾病复发的预测因素.

主要方法:

对140名经过腹腔镜彻底切除的结直肠癌患者的回顾性分析.
在患有和没有复发的患者之间比较基线数据和实验室指标.
随访时间长达3年或直到死亡.

主要成果:

在140名患者中,有30名患者在3年内经历了CRC复发.
复发与低分化的直肠瘤,淋巴侵袭,较低的血清标志物和较低的预后营养指数有关.
中性粒细胞与淋巴细胞的比率升高,细胞素19片段抗原21-1,血管内皮生长因子 (VEGF) 和奇丁酶-3样蛋白1是复发的重要指标.

结论:

多种因素独立地预测腹腔镜手术后结直肠癌复发.
这些已识别的风险因素可以指导临床监测,以减少复发.
基于这些因素的积极监测可能会改善患者的生存结果.

关键词:

结肠直肠癌是一种癌症.laparoscopic 手术拉巴洛斯科普手术是用眼镜进行的手术.复发复发的情况风险因素风险因素

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