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溶性纤维对人血清勒和亚迪波涅丁的影响:系统性审查和剂量反应元分析
Ali Zeinabi1, Hadi Ghaedi1, Seyed Ali Hosseini2
1Department of Sport Physiology, Lamerd Branch, Islamic Azad University, Lamerd 14696-69191, Iran.
Clinical nutrition research
|November 16, 2023
概括
溶性纤维补充剂没有显著改变整体丁或皮内克水平. 然而,它在超重/肥胖个体中显示出对瘦素的益处,在女性和糖尿病患者中显示出对皮素的潜在增加.
科学领域:
- 营养科学 营养科学
- 内分泌学 在内分泌学.
- 代谢健康 代谢健康
背景情况:
- 已知可溶性纤维会影响心脏代谢风险因素.
- 莱普和阿迪波内克丁是代谢调节中的关键激素.
- 以前的文献表明,可溶性纤维与这些激素之间存在联系.
研究的目的:
- 进行一项元分析,评估可溶性纤维补充剂对血清勒丁和阿迪波内克水平的影响.
- 综合现有临床试验的证据.
主要方法:
- 在PubMed,Scopus和ISI Web of Science的系统文献搜索,截至2021年12月.
- 包括符合条件的随机对照试验.
- 应用一个随机效应模型进行元分析.
主要成果:
- 总的来说,与安慰剂相比,可溶性纤维补充剂并没有显著改变皮涅丁或丁度.
- 在超重和肥胖患者中观察到丁的显著改善.
- 在女性和糖尿病小组中,观察到对阿迪波内克的非显著有益趋势.
- 确定了溶性纤维剂量和皮内素水平之间的非线性关联.
结论:
- 溶性纤维补充剂在所有人群中并不能始终改变循环中的勒和阿迪波内克丁水平.
- 对瘦素的有针对性的益处在超重和肥胖个体中是明显的.
- 需要进一步的研究来证实在特定的人口群体中与阿迪波内克相关的潜在益处,并探索剂量-反应关系.
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