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Updated: Jul 11, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
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在卵巢癌患者中检测临床重要的BRCA基因突变,使用下一代测序分析

Yiping Zhang1, Akbar Ali2, Jun Xie1

  • 1School of Life Sciences, Fudan University Shanghai 200438, China.

American journal of cancer research
|November 16, 2023
PubMed
概括

这项研究在巴基斯坦卵巢癌患者中发现了显著的BRCA1/2基因突变,将其与较差的存活率和改变的基因表达联系起来. 这些发现提升了对卵巢癌的理解.

关键词:
这就是BRCA1的原因.这就是BRCA2的原因.卵巢癌是发生在卵巢中的癌症.突变是一种突变.

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