与猪生长表现相关的猪肠道微生物组的比较分析
Jun Hyung Lee1, San Kim1, Eun Sol Kim2
1BRD Korea, Hwaseong 18471, Korea.
Journal of animal science and technology
|November 16, 2023
概括
猪的肠道微生物组组成随着年龄和养殖场环境而变化. 快速生长的猪表现出更高水平的有益细菌,如Bifidobacterium,Clostridium和Lactobacillus.
科学领域:
- 动物科学动物科学
- 微生物学 微生物学
- 基因组学就是基因组学.
背景情况:
- 肠道微生物群在宿主健康中起着至关重要的作用,包括免疫力和病原体抑制.
- 肠道微生物群和牲畜生长表现之间存在着已知的关系.
研究的目的:
- 调查不同农场和不同年龄段的猪生长表现及其肠道微生物群之间的关系.
- 确定特定的肠道微生物群落,与猪的增长率增强有关.
主要方法:
- 16S rRNA基因测序在三个农场的不同年龄的猪 (70,100,130,160天) 的便样本上进行.
- 数据分析使用了对微生物生态学的定量洞察 (QIIME2) 和对元基因组资料的统计分析 (STAMP).
主要成果:
- 肠道微生物群落随着猪年龄的增长出现了显著的变化,显示了类和属的丰富度的变化.
- 虽然多样性指数 (Chao1,OTUs,Shannon) 没有显示出统计差异,但生长速度快的猪的Bifidobacterium,Clostridium和Lactobacillus的丰度更高.
结论:
- 猪肠道微生物群的组成是动态的,受到年龄和农场环境的影响.
- 特定的细菌系,包括Bifidobacterium,Clostridium和Lactobacillus,与猪生长性能的提高有关,为增强提供了潜在的目标.
相关概念视频
01:22Introduction to the Human Microbiota
Microorganisms colonize various regions of the human body, including the mouth, nasal passages, throat, stomach, intestines, urogenital tract, and skin. The total number of microbial cells is estimated to range from 10¹³ to 10¹⁴—comparable to, or exceeding, the number of human somatic cells. This host–microbiome relationship has led to the conceptualization of humans as supraorganisms, wherein microbial communities perform vital roles in development, immunity, and disease...
01:30Development of Human Microbiota
The human microbiota begins developing at birth and undergoes continual change as we age. Infancy marks a critical period of microbial sensitivity, offering a “window of opportunity” during which beneficial microbes help mature the immune system. By age three, children typically develop a more stable and diverse microbial community. Newborns acquire microbes from their immediate environment; vaginal delivery favors maternal vaginal microbes, while cesarean births favor microbes from the skin...
01:27Microbiota of the Stomach and Small Intestine
The human gastrointestinal (GI) tract is characterized by distinct physicochemical conditions that shape its microbial communities. Among these, the stomach presents a particularly challenging environment for microbial colonization due to its highly acidic pH, ranging from 1 to 3. This extreme acidity effectively limits microbial density. However, certain acid-tolerant microorganisms are capable of surviving in this niche. Notably, Helicobacter pylori can colonize the gastric mucosa,...
01:27Microbiota of the Large Intestine
The large intestine hosts the most densely populated microbial ecosystem in the human body. This complex community primarily consists of anaerobic bacteria, with Bacillota (formerly Firmicutes) and Bacteroidota (formerly Bacteroidetes) as the predominant groups. The distribution of these microbes varies along different sections of the large intestine, influenced by local environmental factors such as oxygen availability and nutrient composition.The cecum, located at the beginning of the large...