在完成结核病治疗的成年人肺高血压
B W Allwood1, S Manie2, M Stolbrink1,3
1Division of Pulmonology, Department of Medicine, Faculty of Medicine and Health Sciences, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa.
African journal of thoracic and critical care medicine
|November 16, 2023
概括
肺高血压 (PH) 是结核病 (TB) 治疗后的一个担忧. 这项研究发现,结核病治疗完成的年轻成年人中PH的患病率为4%,这凸显了对这一关联的进一步研究的需要.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 肺高血压 (PH) 结核病 (TB) 后往往被忽视在PH分类中.
- 关于治疗结核病的患者中PH的患病率的数据有限.
研究的目的:
- 确定接近结核病治疗结束的成年患者中PH的患病率.
- 调查PH与患者特征或临床措施之间的潜在关联.
主要方法:
- 一项横截面研究招募了100名接受结核病治疗的患者.
- 胸外心声学评估了右心室缩压 (RVSP).
- 还进行了螺旋测量和6分钟步行测试.
主要成果:
- 观察到PH (RVSP ≥40 mmHg) 或可能PH (RVSP ≥35和<40 mmHg) 的患病率为4%.
- 没有发现PH与性别,年龄,艾滋病毒状况或肺功能之间有显著的关联.
- 吸烟状态与RVSP有相关性,但与PH的存在没有相关性.
结论:
- 在完成结核病治疗的年轻成年人中存在明显的PH患病率.
- 需要进一步进行广泛的研究,以了解结核病和PH之间的联系及其影响.
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