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在使用无效仪器变量进行门德尔随机化的偏差和平均平方误差

Lu Deng1, Sheng Fu2, Kai Yu2

  • 1School of Statistics and Data Science, Nankai University, Tianjin, China.

Genetic epidemiology
|November 16, 2023
PubMed
概括

门德尔随机化 (MR) 使用遗传变异推断因果关系. 本研究提供了公式来评估偏差和平均平方误差 (MSE) 从无效的仪器变量 (IVs) 在两阶段最小平方 (2SLS) MR分析.

关键词:
门德尔的随机化偏见 偏见 偏见 偏见 偏见这是一个仪器变量.平均二次错误的平方值.两个阶段最小平方估计估计.

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