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在家族性和零星性异常性肺纤维化中存在MMP19变异

Yali Fan1,2, Chunming Zheng1,3, Ruimin Ma1

  • 1Clinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, Capital Medical University, No.8 Worker's Stadium, Chaoyang District, Beijing, 100020, China.

Lung
|November 16, 2023
PubMed
概括

在患有异常性肺纤维化 (IPF) 的患者中发现了MMP19基因的遗传变异. 这些MMP19变种增加了IPF风险,存在于家族和零星病例中,为疾病发展提供了新的见解.

关键词:
基因 基因 基因 基因 基因异形性肺纤维化 异形性肺纤维化矩阵金属蛋白酶 19 的作用.变种 变种 变种 变种整体外基因组测序 (Whole-exome Sequencing) 是一种全外基因组测序.

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