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肝功能障碍和心血管风险的生物标志物
Terence B Lee1, Martin T W Kueh2,3, Vardhmaan Jain4
1VCU Health, Department of Internal Medicine, Richmond, VA, USA.
Current cardiology reports
|November 16, 2023
概括
非酒精性脂肪肝疾病 (NAFLD) 越来越多地与心血管疾病 (CVD) 相关. 研究探索NAFLD生物标志物用于预测心血管风险,可能增强未来的风险模型.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 生物标志物研究 生物标志物研究
背景情况:
- 非酒精性脂肪性肝病 (NAFLD) 被认为是心血管疾病 (CVD) 的独立风险因素.
- 2022年美国心脏协会的一份声明强调了这一协会越来越多的证据.
- 新兴研究重点关注NAFLD生物标志物作为心血管风险的预测因素.
研究的目的:
- 审查有关非酒精性脂肪性肝病 (NAFLD) 生物标志物的当前文献.
- 检查NAFLD生物标志物与心血管疾病 (CVD) 结果之间的相关性.
- 评估NAFLD生物标志物与心血管风险评分的相关性.
主要方法:
- 对研究NAFLD生物标志物的文献综述.
- 分析肝脏生物标志物与心血管疾病结局之间的相关性.
- 评估生物标志物与已确定的心血管风险得分的关联.
主要成果:
- 有证据表明NAFLD和CVD之间存在联系,生物标志物显示出潜在的预测价值.
- 一些研究表明,NAFLD生物标志物与心血管风险之间存在显著的关系.
- 然而,存在相互矛盾的发现,一些研究报告没有显著的关联.
结论:
- 在未来,NAFLD生物标志物可能会在预测心血管风险方面发挥作用.
- 这些生物标志物可以作为增加风险的因素或新风险模型的组件.
- 需要进一步的强大和可重复的研究来证实NAFLD生物标志物在心脏病风险评估中的有用性.
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