放射性活性,唾液培养阴性肺结核的治疗:系统性审查和元分析
Adam Thorburn Gray1, Liana Macpherson2, Ffion Carlin1,3
1Institute for Global Health, University College London, London, United Kingdom.
PloS one
|November 16, 2023
概括
多种药物治疗显著降低了患有结核病的放射性证据但阴性唾液培养的个体发展为培养阳性结核病 (TB) 的风险. 需要进一步的研究来确定最佳的治疗策略.
科学领域:
- 肺部医学 肺部医学
- 传染病 传染病 传染病
- 临床试验中的临床试验.
背景情况:
- 具有肺结核 (TB) 放射性证据但阴性唾液培养的个体面临患培养阳性结核病的风险增加.
- 由于扩大了X射线查计划,这种患者群体的识别越来越多.
- 这项研究综合了关于治疗有效性的证据,以防止疾病进展为培养阳性疾病.
结论:
- 多种药物治疗方案显著降低了放射性明显但培养负性结核病患者发展为活跃结核病的风险.
- 然而,大多数包含的研究都已过时,在艾滋病毒流行之前,并使用过时的疗法.
- 新的临床试验对于为这一群体建立最佳治疗方法至关重要.
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