牙周病和根 кариес之间是否存在关联? 一个系统的审查和元分析
Rayssa Maitê Farias Nazário1, Deborah Ribeiro Frazão1, Beatriz Rodrigues Risuenho Peinado1
1Functional and Structural Biology Laboratory, Institute of Biological Sciences, Federal University of Pará, Belém, Brazil.
PloS one
|November 16, 2023
概括
牙周病是一种口腔健康不平衡,与患根的风险更高有关. 这次系统性审查发现了显著的关联,尽管证据的确定性非常低.
科学领域:
- 口腔健康 口腔健康
- 牙周病学 牙周病学
- 牙损 牙损是指牙损的发生.
背景情况:
- 牙周病可以造成口腔健康失衡,可能会促进 cariogenic 细菌.
- 这些不平衡可能会导致根的增加.
研究的目的:
- 系统地审查和分析有关牙周病和根之间的相关性现有证据.
- 量化患有牙周病的个体根的风险.
主要方法:
- 在多个数据库和灰色文献来源中进行了全面的电子搜索.
- 使用PECO策略,包括前性或后性观察性研究.
- 进行随机效应元分析以计算赔率 (OR),评估偏差风险和证据确定性.
主要成果:
- 在最初获取的1,725项研究中,有4项研究符合资格标准.
- 患有牙周病的成年人呈现出明显更高的根的可能性 (OR 1.38 [CI 1.25,1.53]).
- 证据的整体确定性被归类为非常低.
结论:
- 牙周病和根之间存在积极的关联,这得到了定性综合和元分析的支持.
- 由于目前证据的确定性非常低,需要进一步进行高质量的研究.
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