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Updated: Jul 11, 2025

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以效果为导向的分析与非目标查相结合,以识别环境中未被监控的有毒物质

Seongjin Hong1, Junghyun Lee2,3, Jihyun Cha1

  • 1Department of Marine Environmental Science, Chungnam National University, Daejeon 34134, Republic of Korea.

Environmental science & technology
|November 16, 2023
PubMed
概括

以效果为导向的分析 (EDA) 与非目标查 (NTS) 结合,可以识别未被监控的环境毒素. 虽然先进,但这种强大的有毒物质识别工具需要在监测计划中得到更广泛的采用.

关键词:
基于效果的监测基于效果的监测.环境管理环境管理环境监测环境监测环境监测分割 分割 分割 分割 分割 分割 分割 分割 分割 分裂 分裂 分裂 分裂 分裂 分裂 分裂 分裂 分裂 分裂在体外生物测试.没有目标的选.

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Toxic Reactions: Overview01:26

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When toxic substances penetrate the human body, they disseminate to various tissues, undergoing metabolic changes. This process yields reactive metabolites that may covalently bind with specific target molecules, resulting in toxicity.
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
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