动脉替换后的长期结果与最新一代的无牙套假肢
Guglielmo Stefanelli1, Fabio Sgura2, Francesca M Menozzi3
1Department of Cardiac Surgery, Hesperia Hospital, Modena, Italy.
Surgical technology international
|November 16, 2023
概括
第三代无支架大动脉假体表现出卓越的长期临床和血液动力学结果,提供良好的耐用性和不受结构性恶化. 这些门非常适合年轻,活跃的患者和那些患有患者假肢不匹配风险的人.
科学领域:
- 心血管外科心血管外科
- 生物材料科学 生物材料科学
- 医疗器械 医疗器械
背景情况:
- 严重的大动脉病需要大动脉置换 (AVR) 来恢复心脏功能.
- 无支柱心周大动脉假体是AVR的先进选择,旨在改善临床结果.
- 评估第三代无支架门的长期性能对于手术决策至关重要.
研究的目的:
- 评估AVR的长期临床和血液动力学结果,使用第三代无支架心周假体.
- 分析与使用这些先进的大动脉门相关的好处和缺点.
- 为患者选择无支架门植入提供基于证据的建议.
主要方法:
- 一组548名连续患者在2003年至2015年期间使用第三代无支架心周假肢 (3F®和Pericarbon FreedomTM) 进行AVR.
- 收集的数据包括患者人口统计,手术细节 (ECC和十字时间),以及早期/住院结果.
- 长期随访评估了生存率,门功能,结构恶化,内心炎,重新手术和血液动力学表现.
主要成果:
- 整个队列的早期死亡率为2.55%,孤立AVR的早期死亡率为0.91%. 随访时间中位数为6.77年.
- 在12年内,心脏存活率为91%,所有幸存者都属于NYHA I级. 没有结构损坏的情况为86%.
- 在12年内,无内心炎和重新手术的比例为95%,平均残留梯度为10.3mmHg.
结论:
- 第三代无支架心膜提供了优良的血液动力学和耐用性,在12年内没有结构性恶化.
- 虽然植入比支架门要求稍高,但它很容易在最少的训练下复制.
- 这些门推用于年轻,活跃的患者和身体表面积大的人,以避免患者与假肢不匹配.
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