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Updated: Jul 11, 2025

Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres
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Discovery of Driver Genes in Colorectal HT29-derived Cancer Stem-Like Tumorspheres

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全基因组测序和RNA测序分析揭示了肝细胞瘤中新的风险基因和差异性表达模式

Wuqian Wang1, Na Zhang2, Luan Chen2

  • 1Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai 200030, China; Jiaxing Maternity and Children Health Care Hospital, Affiliated Women and Children Hospital Jiaxing University, Jiaxing, Zhejiang, China.

Gene
|November 16, 2023
PubMed
概括

对儿童肝母细胞瘤 (HB) 的基因组分析揭示了CTNNB1,AXIN2和PARP1的关键突变,以及BRCA2和GPC3.3等新型潜在风险基因. 这项研究促进了对儿科肝癌机制的理解.

关键词:
遗传学 遗传学 是一个肝炎母细胞瘤是什么?在RNA-seqqq.在WGS中,使用的是WGS.

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相关概念视频

Ribosome Profiling02:24

Ribosome Profiling

Ribosome profiling or ribo-sequencing is a deep sequencing technique that produces a snapshot of active translation in a cell. It selectively sequences the mRNAs protected by ribosomes to get an insight into a cell’s translation landscape at any given point in time.
Applications of ribosome profiling
Ribosome profiling has many applications, including in vivo monitoring of translation inside a particular organ or tissue type and quantifying new protein synthesis levels.
The technique...
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