度匹配在避免压力屏蔽引起的骨损失和压力度引起的骨重建装置故障中的作用
Agnieszka Chmielewska1, David Dean2
1The Department of Materials Science and Engineering, The Ohio State University, Columbus, OH 43210, USA.
Acta biomaterialia
|November 16, 2023
概括
硬度匹配的骨重建设备通过模仿自然骨负荷来减少植入物失败. 本综述探讨了最佳设计,以防止压力屏蔽,并改善长期的骨愈合和植入物生存.
科学领域:
- 生物材料科学 生物材料科学
- 整形外科工程 整形外科工程
- 医疗器械设计 医疗器械设计
背景情况:
- 过于硬的骨科植入物可能导致机械故障,并需要修复手术.
- 标准植入物可能会导致压力屏蔽和压力度,阻碍长期的骨愈合和植入物寿命.
研究的目的:
- 审查最近在设计具有优化机械性能的骨重建装置方面的进展.
- 突出实现植入物硬度匹配的策略,以改善骨整合和负载传导.
主要方法:
- 审查关于骨架重建设备设计的当前研究.
- 分析影响机械性能的因素:材料,几何,位置和表面特性.
- 探索辅助性材料,梯度孔隙性和表面修饰以增强骨质整合.
主要成果:
- 最佳的设备设计包括调整位置,集成,材料,几何和表面特性.
- 度匹配旨在在愈合过程中限制骨的压力,并尽量减少愈合后正常负载模式的破坏.
- 技术包括使用骨状模量材料,适应几何学和表面修改,以更好地转移负载.
结论:
- 刚度匹配的植入物对于减轻应力屏蔽和应力度至关重要,这是金属设备故障的常见原因.
- 先进的设计策略促进可持续的压力-应变关系,以有效地修复和维护骨.
- 这些进展提高了骨科重建的长期性能和患者的结果.
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