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关于PGRMC1对人类子宫内膜细胞中循环AMP介导的COX2表达的监管行动

Atsuya Tsuru1, Mikihiro Yoshie1, Ryota Negishi1

  • 1Department of Endocrine Pharmacology, Tokyo University of Pharmacy and Life Sciences, Tokyo 192-0392, Japan.

Journal of pharmacological sciences
|November 16, 2023
PubMed
概括

孕激素受体膜成分1 (PGRMC1) 的下调增强子宫内膜细胞分化 (二分化) 通过增加循环氧化酶2 (COX2) 表达. 这个过程涉及FOXO1和NF-κB信号通路.

关键词:
循环氧基因酶2 (COX2) 的作用.决心实现二元化子宫内膜 (Endometrium) 是一个内膜.叉头盒子蛋白O1 (FOXO1) 是一种分叉头盒子蛋白.孕激素受体膜组成部分1 (PGRMC1)

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