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在治疗计划系统中实施的新型CBCT转换方法的评估

Wolfgang Lechner¹, Dávid Kanalas², Sarah Haupt²

¹Division of Medical Radiation Physics, Department of Radiation Oncology, Medical University of Vienna/AKH Vienna, Währinger Gürtel 18-20, 1090, Vienna, Austria. Wolfgang.lechner@meduniwien.ac.at.

Radiation oncology (London, England)

|November 17, 2023

概括

一个新的CBCT转换算法 (CBCTc) 提高了治疗计划系统中剂量计算的准确性. 这种新的方法优于散密重置技术 (CBCTb),特别是在空气/组织接口附近.

科学领域:

医学物理医学物理
辐射瘤学辐射瘤学
图像指导疗法是指导图像的疗法.

背景情况:

圆束计算断层扫描 (CBCT) 对于图像导向放射治疗至关重要.
在CBCT中精确的剂量计算对于有效的癌症治疗至关重要.
需要新的算法来改进基于CBCT的剂量计算.

研究的目的:

评估用于剂量计算的新型CBCT转换算法.
为了比较其性能与大量密度超越技术.
评估解剖学变异对剂量分配的影响.

主要方法:

在研究治疗计划系统中实施了新的CBCT转换算法 (CBCTc).
收集了来自头,妇科和肺癌患者的CBCT数据.
使用散密度重置方法 (CBCTb) 和使用马分析的变形CT (dCT) 进行了CBCTc的比较.

主要成果:

通过CBCTc方法,比通过CBCTb方法系统地显示出更高的马传递率 (GPRs).
对CBCTc的中位数GPR为100% (HN),99.8% (GYN) 和99.9% (LNG).
由于解剖学变异,观察到显著的差异,特别是在空气/组织接口附近.

结论:

新的CBCTc算法与计划CT (pCT) 和变形CT (dCT) 的剂量计算提供了出色的一致性.
在剂量分配准确性方面,CBCTc显著优于CBCTb方法.
解剖学变化仍然是影响剂量计算偏差的一个关键因素.

关键词:

准确度准确度准确度准确度准确度适应性辐射疗法适应性辐射疗法基于CBCT的剂量计算可变形的注册表可以变形.

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