氧气治疗持续时间对认知障碍的影响 住院治疗SARS-COV-2感染12个月后的认知障碍12个月后
Amandine Rapin1, Arnaud Calmus2, Charles Pradeau3
1Department of Physical and Rehabilitation Medicine, hôpital Sebastopol, Reims, France; Faculty of Medicine, Reims Champagne-Ardenne University, MATIM, Reims, France VieFra, EA3797, Reims, France. arapin@chu-reims.fr.
Journal of rehabilitation medicine
|November 17, 2023
概括
持续性认知障碍影响超过一半的住院COVID-19患者在12个月. 较短的氧气治疗持续时间和较高的早期迷你精神状态检查 (MMSE) 评分预测了更好的认知结果.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 康复医学 康复医学 康复医学
背景情况:
- COVID-19 (SARS-CoV-2) 感染可能导致长期的神经系统连续性.
- 认知障碍是许多COVID-19幸存者的住院后严重并发症.
研究的目的:
- 确定COVID-19住院治疗12个月后持续认知障碍的预测因素.
- 评估急性护理参数与长期认知功能之间的关联.
主要方法:
- 对56名因COVID-19住院的患者进行了回顾性单中心研究.
- 6个月和12个月的神经心理检测 (NPT),包括3个月的迷你精神状态检查 (MMSE).
- 后勤回归和ROC曲线分析以确定认知障碍的预测因素.
主要成果:
- 64.3%和53.6%的患者在6个月和12个月分别表现出认知障碍.
- 注意力和处理速度是12个月后受影响最严重的认知领域.
- 氧气治疗的持续时间和3个月的MMSE得分是12个月认知障碍的显著预测因素.
结论:
- 大约一半的住院COVID-19患者在感染后一年经历认知障碍.
- 在急性疾病期间,较短时间的氧气治疗可能是保护因素.
- 3个月的早期MMSE查可以帮助识别患有持续认知缺陷的风险人群.
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