内镜切除治疗状骨病变的可行性和安全性
Li Wang1,2, Zu-Qiang Liu1,2, Ji-Yuan Zhang1,2
1Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai, China.
Journal of gastroenterology and hepatology
|November 17, 2023
概括
脊椎病变 (JIL) 的内镜切除 (ER) 是可行的和安全的,显示了短期和长期的有利结果. 内镜下粘膜切割 (ESD) 和内镜粘膜切除 (EMR) 两种方法都能有效地治疗在被选中的患者中的JIL.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 手术瘤学手术瘤学
背景情况:
- 脊椎病变 (JILs) 的内镜切除 (ER) 提出了重大的技术挑战.
- 鉴定ER对JIL的临床病理特征,可行性和安全性对于改善患者的治疗结果至关重要.
研究的目的:
- 评估内镜切除对节病变的临床病理学特征,可行性和安全性.
- 为了比较结肠镜和肠镜切除之间的结果,以及内镜下粘膜切除 (ESD) 和内镜粘膜切除 (EMR) 之间的JILs.
主要方法:
- 在2012年1月至2022年2月期间为JILs接受ER的52名患者的回顾性分析.
- 收集的数据包括临床病理学特征,程序参数,结果和随访.
- 病变的分类是基于相对于大脑膜的位置,确定内镜方法 (结肠镜与肠镜).
主要成果:
- 该研究包括52名患者,平均年龄为49.4岁.
- 结肠镜检查了距离大脑膜20厘米以内的33个病变;肠镜检查了距离大脑膜更远的19个病变.
- 整体切除率和R0切除率分别为86.5%和84.6%. 不良事件 (AEs) 较低 (1.9%主要,9.6%轻微). 无复发5年生存率 (RFS) 和疾病特异性生存率 (DSS) 分别为92.9%和94.1%.
- 结肠镜组的副作用明显低于肠镜组 (P < 0.05),在RFS或DSS方面没有显著差异.
- 在ESD和EMR技术之间没有观察到AE,RFS或DSS的显著差异.
结论:
- 结核叶病变的内镜切除显示了有利的短期和长期临床结果.
- 内镜下粘膜切割 (ESD) 和内镜粘膜切除 (EMR) 都是适当选择的头膜病变的安全和有效的治疗选择.
- JILs的ER是一种可行的,安全的治疗方式,具有良好的瘤治疗结果.
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